PURPOSE:o summarize current urologic measures in the diagnosis of prostate cancer.
MATERIALS AND METHODS: Current urologic literatures were evaluated.
RESULTS: Prostate-specific antigen(PSA) is now a routine part of the investigation of men with suspected prostate cancer. While a very useful test, it still has its problems, in particular its lack of specificity. Since PSA may overlap in men with and without prostate cancer, other derivatives of PSA were developed to enhance the ability for detecting early stage prostate cancer. To date, for the initial biopsy, the optimal number of biopsy core for detecting prostate cancer remains controversial. Furthermore, it is also unclear who should undergo a repeat biopsy and when to stop biopsying.
CONCLUSIONS: This review describes the current problems with PSA testing in prostate cancer diagnosis and highlights potential ways in which these may be reduced. In addition, although there is no universally accepted technique of prostate biopsy, the current literature supports use of more extensive biopsy techniques to increase the likelihood of prostate cancer detection.(Korean J Urol 2004;45:197-208)
|